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Slow Delayed Rectifier Current Protects Ventricular Myocytes from Arrhythmic Dynamics Across Multiple Species: A Computational Study

BACKGROUND: The slow and rapid delayed rectifier K(+) currents (I(Ks) and I(Kr), respectively) are responsible for repolarizing the ventricular action potential (AP) and preventing abnormally long APs that may lead to arrhythmias. Although differences in biophysical properties of the two currents ha...

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Detalhes bibliográficos
Publicado no:Circ Arrhythm Electrophysiol
Main Authors: Varshneya, Meera, Devenyi, Ryan A., Sobie, Eric A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326778/
https://ncbi.nlm.nih.gov/pubmed/30354408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.118.006558
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