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Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine
Extensive 3′ alternative splicing of the mu opioid receptor gene OPRM1 creates multiple C-terminal splice variants. However, their behavioral relevance remains unknown. The present study generated 3 mutant mouse models with truncated C termini in 2 different mouse strains, C57BL/6J (B6) and 129/SvEv...
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Pubblicato in: | J Clin Invest |
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Autori principali: | , , , , , , , , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
American Society for Clinical Investigation
2017
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5373896/ https://ncbi.nlm.nih.gov/pubmed/28319053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88760 |
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