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Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions
Heroin remains a major drug of abuse and is preferred by addicts over morphine. Like morphine, heroin has high affinity and selectivity for μ-receptors, but its residual analgesia in exon 1 MOR-1 knockout mice that do not respond to morphine suggests a different mechanism of action. MOR-1 splice var...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660730/ https://ncbi.nlm.nih.gov/pubmed/19273844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811586106 |
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