Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability

Kidney podocytes’ function depends on fingerlike projections (foot processes) that interdigitate with those from neighboring cells to form the glomerular filtration barrier. The integrity of the barrier depends on spatial control of dynamics of actin cytoskeleton in the foot processes. We determined...

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Foilsithe in:PLoS Comput Biol
Main Authors: Falkenberg, Cibele V., Azeloglu, Evren U., Stothers, Mark, Deerinck, Thomas J., Chen, Yibang, He, John C., Ellisman, Mark H., Hone, James C., Iyengar, Ravi, Loew, Leslie M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373631/
https://ncbi.nlm.nih.gov/pubmed/28301477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005433
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