Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability

Kidney podocytes’ function depends on fingerlike projections (foot processes) that interdigitate with those from neighboring cells to form the glomerular filtration barrier. The integrity of the barrier depends on spatial control of dynamics of actin cytoskeleton in the foot processes. We determined...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Falkenberg, Cibele V., Azeloglu, Evren U., Stothers, Mark, Deerinck, Thomas J., Chen, Yibang, He, John C., Ellisman, Mark H., Hone, James C., Iyengar, Ravi, Loew, Leslie M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373631/
https://ncbi.nlm.nih.gov/pubmed/28301477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005433
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