Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability

Kidney podocytes’ function depends on fingerlike projections (foot processes) that interdigitate with those from neighboring cells to form the glomerular filtration barrier. The integrity of the barrier depends on spatial control of dynamics of actin cytoskeleton in the foot processes. We determined...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Falkenberg, Cibele V., Azeloglu, Evren U., Stothers, Mark, Deerinck, Thomas J., Chen, Yibang, He, John C., Ellisman, Mark H., Hone, James C., Iyengar, Ravi, Loew, Leslie M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373631/
https://ncbi.nlm.nih.gov/pubmed/28301477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005433
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