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X chromosome inactivation: new players in the initiation of gene silencing

X chromosome inactivation (XCI) is a dosage compensation process that was adopted by female mammals to balance gene dosage between XX females and XY males. XCI starts with the upregulation of the non-coding RNA Xist, after which most X-linked genes are silenced and acquire a repressive chromatin sta...

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Détails bibliographiques
Publié dans:F1000Res
Auteurs principaux: Pinheiro, Ines, Heard, Edith
Format: Artigo
Langue:Inglês
Publié: F1000Research 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373419/
https://ncbi.nlm.nih.gov/pubmed/28408975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.10707.1
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