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Substrate Trapping in the Siderophore Tailoring Enzyme PvdQ
Siderophore biosynthesis by Pseudomonas aeruginosa enhances virulence and represents an attractive drug target. PvdQ functions in the type-1 pyoverdine biosynthetic pathway by removing a myristoyl anchor from a pyoverdine precursor, allowing eventual release from the periplasm. A circularly permuted...
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Publicado no: | ACS Chem Biol |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5373092/ https://ncbi.nlm.nih.gov/pubmed/28186406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00031 |
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