Identification of Inhibitors of PvdQ, an Enzyme Involved in the Synthesis of the Siderophore Pyoverdine

[Image: see text] Pseudomonas aeruginosa produces the peptide siderophore pyoverdine, which is used to acquire essential Fe(3+) ions from the environment. PvdQ, an Ntn hydrolase, is required for the biosynthesis of pyoverdine. PvdQ knockout strains are not infectious in model systems, suggesting tha...

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Autori principali: Wurst, Jacqueline M., Drake, Eric J., Theriault, Jimmy R., Jewett, Ivan T., VerPlank, Lynn, Perez, Jose R., Dandapani, Sivaraman, Palmer, Michelle, Moskowitz, Samuel M., Schreiber, Stuart L., Munoz, Benito, Gulick, Andrew M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215858/
https://ncbi.nlm.nih.gov/pubmed/24824984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5001586
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