Identification of Inhibitors of PvdQ, an Enzyme Involved in the Synthesis of the Siderophore Pyoverdine

[Image: see text] Pseudomonas aeruginosa produces the peptide siderophore pyoverdine, which is used to acquire essential Fe(3+) ions from the environment. PvdQ, an Ntn hydrolase, is required for the biosynthesis of pyoverdine. PvdQ knockout strains are not infectious in model systems, suggesting tha...

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Detalhes bibliográficos
Main Authors: Wurst, Jacqueline M., Drake, Eric J., Theriault, Jimmy R., Jewett, Ivan T., VerPlank, Lynn, Perez, Jose R., Dandapani, Sivaraman, Palmer, Michelle, Moskowitz, Samuel M., Schreiber, Stuart L., Munoz, Benito, Gulick, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215858/
https://ncbi.nlm.nih.gov/pubmed/24824984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5001586
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