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Retinoic Acid Negatively Impacts Proliferation and MC(TC) Specific Attributes of Human Skin Derived Mast Cells, but Reinforces Allergic Stimulability

The Vitamin-A-metabolite retinoic acid (RA) acts as a master regulator of cellular programs. Mast cells (MCs) are primary effector cells of type-I-allergic reactions. We recently uncovered that human cutaneous MCs are enriched with RA network components over other skin cells. Yet, direct experimenta...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Babina, Magda, Artuc, Metin, Guhl, Sven, Zuberbier, Torsten
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372541/
https://ncbi.nlm.nih.gov/pubmed/28264498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18030525
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