A Novel Cell Culture System to Improve MRGPRX2 Research in Human Skin Mast Cells
ABSTRACT Background MRGPRX2, a receptor central to mast cell (MC) activation and related skin diseases, is selectively expressed in skin MCs but downregulated during culture by stem cell factor (SCF) and interleukin‐4 (IL‐4). Objective To identify culture conditions that preserve MC viability while...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Wiley
2025-10-01
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| Series: | Clinical and Translational Allergy |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/clt2.70112 |
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