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A Novel Cell Culture System to Improve MRGPRX2 Research in Human Skin Mast Cells

ABSTRACT Background MRGPRX2, a receptor central to mast cell (MC) activation and related skin diseases, is selectively expressed in skin MCs but downregulated during culture by stem cell factor (SCF) and interleukin‐4 (IL‐4). Objective To identify culture conditions that preserve MC viability while...

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Principais autores: Zhuoran Li, Jean Schneikert, Anja Wegner, Torsten Zuberbier, Magda Babina
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2025-10-01
Series:Clinical and Translational Allergy
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Acceso en liña:https://doi.org/10.1002/clt2.70112
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