Thermal energy suppresses mutational defects in DNA unwinding at a yeast replication origin.

Yeast replication origins contain a DNA sequence element whose biological activity correlates with hypersensitivity to single-strand-specific nucleases in negatively supercoiled plasmids. By using two-dimensional gel electrophoresis of plasmid topoisomers, we demonstrate that thermodynamically stabl...

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Hauptverfasser: Umek, R M, Kowalski, D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC53714/
https://ncbi.nlm.nih.gov/pubmed/2181439
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