Thermal energy suppresses mutational defects in DNA unwinding at a yeast replication origin.

Yeast replication origins contain a DNA sequence element whose biological activity correlates with hypersensitivity to single-strand-specific nucleases in negatively supercoiled plasmids. By using two-dimensional gel electrophoresis of plasmid topoisomers, we demonstrate that thermodynamically stabl...

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Bibliographic Details
Main Authors: Umek, R M, Kowalski, D
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC53714/
https://ncbi.nlm.nih.gov/pubmed/2181439
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