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Thermal energy suppresses mutational defects in DNA unwinding at a yeast replication origin.

Yeast replication origins contain a DNA sequence element whose biological activity correlates with hypersensitivity to single-strand-specific nucleases in negatively supercoiled plasmids. By using two-dimensional gel electrophoresis of plasmid topoisomers, we demonstrate that thermodynamically stabl...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Umek, R M, Kowalski, D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53714/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2181439/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.7.2486
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