Thermal energy suppresses mutational defects in DNA unwinding at a yeast replication origin.
Yeast replication origins contain a DNA sequence element whose biological activity correlates with hypersensitivity to single-strand-specific nucleases in negatively supercoiled plasmids. By using two-dimensional gel electrophoresis of plasmid topoisomers, we demonstrate that thermodynamically stabl...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2181439/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.7.2486 |
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