Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma

BACKGROUND: Colorectal adenocarcinomas are characterized by abnormal mitochondrial DNA (mtDNA) copy number and genomic instability, but a molecular interaction between mitochondrial and nuclear genome remains unknown. Here we report the discovery of increased copies of nuclear mtDNA (NUMT) in colore...

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Dades bibliogràfiques
Publicat a:Genome Med
Autors principals: Srinivasainagendra, Vinodh, Sandel, Michael W., Singh, Bhupendra, Sundaresan, Aishwarya, Mooga, Ved P., Bajpai, Prachi, Tiwari, Hemant K., Singh, Keshav K.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370490/
https://ncbi.nlm.nih.gov/pubmed/28356157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0420-6
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