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Epigenetic modification of miR-663 controls mitochondria-to-nucleus retrograde signaling and tumor progression

The normal cellular function requires communication between mitochondria and the nucleus, termed mitochondria-to-nucleus retrograde signaling. Disruption of this mechanism has been implicated in the development of cancers. Many proteins are known modulators of retrograde signaling, but whether micro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Carden, Trevor, Singh, Bhupendra, Mooga, Ved, Bajpai, Prachi, Singh, Keshav K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733605/
https://ncbi.nlm.nih.gov/pubmed/29066618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.797001
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