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Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function

Mitochondrial DNA (mtDNA) depletion is involved in mtDNA depletion syndromes, mitochondrial diseases, aging and aging-associated chronic diseases, and other human pathologies. To evaluate the consequences of depletion of mtDNA in the whole animal, we created an inducible mtDNA-depleter mouse express...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Singh, Bhupendra, Schoeb, Trenton R., Bajpai, Prachi, Slominski, Andrzej, Singh, Keshav K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053453/
https://ncbi.nlm.nih.gov/pubmed/30026579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0765-9
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