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Inhibition of glycosphingolipid synthesis reverses skin inflammation and hair loss in ApoE−/− mice fed western diet

Sphingolipids have been accorded numerous biological functions however, the effects of feeding a western diet (diet rich in cholesterol and fat) on skin phenotypes, and color is not known. Here, we observed that chronic high-fat and high-cholesterol diet intake in a mouse model of atherosclerosis (A...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bedja, Djahida, Yan, Wenwen, Lad, Viren, Iocco, Domenica, Sivakumar, Nickash, Bandaru, Veera Venkata Ratnam, Chatterjee, Subroto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065400/
https://ncbi.nlm.nih.gov/pubmed/30061606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28663-9
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