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Prevention of Cardiac Hypertrophy by the Use of a Glycosphingolipid Synthesis Inhibitor in ApoE−/− Mice
ApoE−/− mice fed a high fat and high cholesterol (HFHC) diet (20% fat and 1.25% cholesterol) from 12 weeks of age to 36 weeks revealed an age-dependent increase in the left ventricular mass (LV mass) and decline in fractional shortening (FS%), which worsened with HFHC diet. These traits are indicati...
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| Veröffentlicht in: | Biochem Biophys Res Commun |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4888073/ https://ncbi.nlm.nih.gov/pubmed/26253472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.07.159 |
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