Prevention of Cardiac Hypertrophy by the Use of a Glycosphingolipid Synthesis Inhibitor in ApoE−/− Mice

ApoE−/− mice fed a high fat and high cholesterol (HFHC) diet (20% fat and 1.25% cholesterol) from 12 weeks of age to 36 weeks revealed an age-dependent increase in the left ventricular mass (LV mass) and decline in fractional shortening (FS%), which worsened with HFHC diet. These traits are indicati...

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Vydáno v:Biochem Biophys Res Commun
Hlavní autoři: Mishra, Sumita, Bedja, Djahida, Amuzie, Christine, Avolio, Alberto, Chatterjee, Subroto
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888073/
https://ncbi.nlm.nih.gov/pubmed/26253472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.07.159
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