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Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism

BACKGROUND: Dietary restriction (DR), a reduction in food intake without malnutrition, increases most aspects of health during aging and extends lifespan in diverse species, including rodents. However, the mechanisms by which DR interacts with the aging process to improve health in old age are poorl...

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Bibliographische Detailangaben
Veröffentlicht in:Genome Biol
Hauptverfasser: Hahn, Oliver, Grönke, Sebastian, Stubbs, Thomas M., Ficz, Gabriella, Hendrich, Oliver, Krueger, Felix, Andrews, Simon, Zhang, Qifeng, Wakelam, Michael J., Beyer, Andreas, Reik, Wolf, Partridge, Linda
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370449/
https://ncbi.nlm.nih.gov/pubmed/28351387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1187-1
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