Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism

BACKGROUND: Dietary restriction (DR), a reduction in food intake without malnutrition, increases most aspects of health during aging and extends lifespan in diverse species, including rodents. However, the mechanisms by which DR interacts with the aging process to improve health in old age are poorl...

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Bibliographic Details
Published in:Genome Biol
Main Authors: Hahn, Oliver, Grönke, Sebastian, Stubbs, Thomas M., Ficz, Gabriella, Hendrich, Oliver, Krueger, Felix, Andrews, Simon, Zhang, Qifeng, Wakelam, Michael J., Beyer, Andreas, Reik, Wolf, Partridge, Linda
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370449/
https://ncbi.nlm.nih.gov/pubmed/28351387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1187-1
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