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Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity
Dietary, pharmacological and genetic interventions can extend health- and lifespan in diverse mammalian species. DNA methylation has been implicated in mediating the beneficial effects of these interventions; methylation patterns deteriorate during ageing, and this is prevented by lifespan-extending...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6281273/ https://ncbi.nlm.nih.gov/pubmed/30462643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007766 |
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