Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity

Dietary, pharmacological and genetic interventions can extend health- and lifespan in diverse mammalian species. DNA methylation has been implicated in mediating the beneficial effects of these interventions; methylation patterns deteriorate during ageing, and this is prevented by lifespan-extending...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Hahn, Oliver, Stubbs, Thomas M., Reik, Wolf, Grönke, Sebastian, Beyer, Andreas, Partridge, Linda
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281273/
https://ncbi.nlm.nih.gov/pubmed/30462643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007766
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