A nutritional memory effect counteracts benefits of dietary restriction in old mice

Dietary restriction (DR) during adulthood can greatly extend lifespan and improve metabolic health in diverse species. However, whether DR in mammals is still effective when applied for the first time at old age remains elusive. Here, we report results of a late-life DR switch experiment employing 8...

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Pubblicato in:Nat Metab
Autori principali: Hahn, Oliver, Drews, Lisa F., Nguyen, An, Tatsuta, Takashi, Gkioni, Lisonia, Hendrich, Oliver, Zhang, Qifeng, Langer, Thomas, Pletcher, Scott, Wakelam, Michael J. O., Beyer, Andreas, Grönke, Sebastian, Partridge, Linda
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861129/
https://ncbi.nlm.nih.gov/pubmed/31742247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-019-0121-0
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