Multi-drug loaded micelles delivering chemotherapy and targeted therapies directed against HSP90 and the PI3K/AKT/mTOR pathway in prostate cancer

BACKGROUND: Advanced prostate cancers that are resistant to all current therapies create a need for new therapeutic strategies. One recent innovative approach to cancer therapy is the simultaneous use of multiple FDA-approved drugs to target multiple pathways. A challenge for this approach is caused...

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Publicado en:PLoS One
Autores principales: Le, Bao, Powers, Ginny L., Tam, Yu Tong, Schumacher, Nicholas, Malinowski, Rita L., Steinke, Laura, Kwon, Glen, Marker, Paul C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370140/
https://ncbi.nlm.nih.gov/pubmed/28350865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174658
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