Doxycycline directly targets PAR1 to suppress tumor progression

Doxycycline have been reported to exert anti-cancer activity and have been assessed as anti-cancer agents in clinical trials. However, the direct targets of doxycycline in cancer cells remain unclear. In this study, we used a chemical proteomics approach to identify the Protease-activated receptor 1...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhong, Weilong, Chen, Shuang, Zhang, Qiang, Xiao, Ting, Qin, Yuan, Gu, Ju, Sun, Bo, Liu, Yanrong, Jing, Xiangyan, Hu, Xuejiao, Zhang, Peng, Zhou, Honggang, Sun, Tao, Yang, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370004/
https://ncbi.nlm.nih.gov/pubmed/28187433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15166
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