Doxycycline reverses epithelial-to-mesenchymal transition and suppresses the proliferation and metastasis of lung cancer cells

The gelatinase inhibitor doxycycline is the prototypical antitumor antibiotic. We investigated the effects of doxycycline on the migration, invasion, and metastasis of human lung cancer cell lines and in a mouse model. We also measured the effect of doxycycline on the transcription of epithelial-mes...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Qin, Yuan, Zhang, Qiang, Lee, Shan, Zhong, Wei-long, Liu, Yan-rong, Liu, Hui-juan, Zhao, Dong, Chen, Shuang, Xiao, Ting, Meng, Jing, Jing, Xue-shuang, Wang, Jing, Sun, Bo, Dai, Ting-ting, Yang, Cheng, Sun, Tao, Zhou, Hong-gang
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747360/
https://ncbi.nlm.nih.gov/pubmed/26512779
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