HIPK2-T566 autophosphorylation diversely contributes to UV- and doxorubicin-induced HIPK2 activation

HIPK2 is a Y-regulated S/T kinase involved in various cellular processes, including cell-fate decision during development and DNA damage response. Cis-autophosphorylation in the activation-loop and trans-autophosphorylation at several S/T sites along the protein are required for HIPK2 activation, su...

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Vydáno v:Oncotarget
Hlavní autoři: Verdina, Alessandra, Di Rocco, Giuliana, Virdia, Ilaria, Monteonofrio, Laura, Gatti, Veronica, Policicchio, Eleonora, Bruselles, Alessandro, Tartaglia, Marco, Soddu, Silvia
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369998/
https://ncbi.nlm.nih.gov/pubmed/28060750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14421
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