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HIPK2 catalytic activity and subcellular localization are regulated by activation-loop Y354 autophosphorylation
HIPK2 (homeodomain-interacting protein kinase-2) binds to and phosphorylates, at Ser and Thr residues, a large number of targets involved in cell division and cell fate decision in response to different physiological or stress stimuli. Inactivation of HIPK2 has been observed in human and mouse cance...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Pub. Co
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3787740/ https://ncbi.nlm.nih.gov/pubmed/23485397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2013.02.018 |
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