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Near infrared fluorescent imaging of choline kinase alpha expression and inhibition in breast tumors

Choline kinase alpha (ChoKα) overexpression is associated with an aggressive tumor phenotype. ChoKα inhibitors induce apoptosis in tumors, however validation of their specificity is difficult in vivo. We report the use of optical imaging to assess ChoKα status in cells and in vivo using JAS239, a ca...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Arlauckas, Sean P., Kumar, Manoj, Popov, Anatoliy V., Poptani, Harish, Delikatny, Edward J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369982/
https://ncbi.nlm.nih.gov/pubmed/28157707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14965
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