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Near infrared fluorescent imaging of choline kinase alpha expression and inhibition in breast tumors
Choline kinase alpha (ChoKα) overexpression is associated with an aggressive tumor phenotype. ChoKα inhibitors induce apoptosis in tumors, however validation of their specificity is difficult in vivo. We report the use of optical imaging to assess ChoKα status in cells and in vivo using JAS239, a ca...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5369982/ https://ncbi.nlm.nih.gov/pubmed/28157707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14965 |
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