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Near infrared fluorescent imaging of choline kinase alpha expression and inhibition in breast tumors

Choline kinase alpha (ChoKα) overexpression is associated with an aggressive tumor phenotype. ChoKα inhibitors induce apoptosis in tumors, however validation of their specificity is difficult in vivo. We report the use of optical imaging to assess ChoKα status in cells and in vivo using JAS239, a ca...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Arlauckas, Sean P., Kumar, Manoj, Popov, Anatoliy V., Poptani, Harish, Delikatny, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369982/
https://ncbi.nlm.nih.gov/pubmed/28157707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14965
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