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Magnetic resonance spectroscopy for detection of choline kinase inhibition in the treatment of brain tumors

Abnormal choline metabolism is a hallmark of cancer and is associated with oncogenesis and tumor progression. Increased choline is consistently observed in both pre-clinical tumor models and in human brain tumors by proton magnetic resonance spectroscopy (MRS). Thus, inhibition of choline metabolism...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Kumar, Manoj, Arlauckas, Sean P., Saksena, Sona, Verma, Gaurav, Ittyerah, Ranjit, Pickup, Stephen, Popov, Anatoliy V., Delikatny, Edward J., Poptani, Harish
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394035/
https://ncbi.nlm.nih.gov/pubmed/25657334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0775
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