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Magnetic resonance spectroscopy of the occipital cortex and the cerebellar vermis distinguishes individual cats affected with alpha-mannosidosis from normal cats

A genetic deficiency of lysosomal alpha-mannosidase causes the lysosomal storage disease alpha-mannosidosis (AMD), in which oligosaccharide accumulation occurs in neurons and glia. The purpose of this study was to evaluate the role of magnetic resonance spectroscopy (MRS) in detecting the oligosacch...

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Detalhes bibliográficos
Main Authors: Magnitsky, Sergey, Vite, Charles H., Delikatny, Edward J., Pickup, Stephen, Wehrli, Suzanne, Wolfe, John H., Poptani, Harish
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045771/
https://ncbi.nlm.nih.gov/pubmed/19743435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.1430
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