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Platinum-Catalyzed α,β-Unsaturated Carbene Formation in the Formal Syntheses of Frondosin B and Liphagal

Formal syntheses of tetracyclic terpenoids frondosin B and liphagal are described. Both synthetic routes rely on the use of platinum-catalyzed α,β-unsaturated carbene formation for the key C–C bond forming transformations. The successful route toward frondosin B utilizes a formal (4 + 3) cycloadditi...

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Detalles Bibliográficos
Publicado en:Org Lett
Autores principales: Huynh, Khoi Q., Seizert, Curtis A., Ozumerzifon, Tarik J., Allegretti, Paul A., Ferreira, Eric M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369019/
https://ncbi.nlm.nih.gov/pubmed/27997203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b03682
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