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Copper-catalyzed enantioselective conjugate reduction of α,β-unsaturated esters with chiral phenol–carbene ligands

A chiral phenol–NHC ligand enabled the copper-catalyzed enantioselective conjugate reduction of α,β-unsaturated esters. The phenol moiety of the chiral NHC ligand played a critical role in producing the enantiomerically enriched products. The catalyst worked well for various (Z)-isomer substrates. O...

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Dades bibliogràfiques
Publicat a:Beilstein J Org Chem
Autors principals: Mimura, Shohei, Mizushima, Sho, Shimizu, Yohei, Sawamura, Masaya
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136546/
https://ncbi.nlm.nih.gov/pubmed/32280383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.16.50
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