Evaluation of helper-dependent canine adenovirus vectors in a 3D human CNS model

Gene therapy is a promising approach with enormous potential for treatment of neurodegenerative disorders. Viral vectors derived from canine adenovirus type 2 (CAV-2) present attractive features for gene delivery strategies in the human brain, by preferentially transducing neurons, are capable of ef...

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Veröffentlicht in:Gene Ther
Hauptverfasser: Simão, Daniel, Pinto, Catarina, Fernandes, Paulo, Peddie, Christopher J., Piersanti, Stefania, Collinson, Lucy M., Salinas, Sara, Saggio, Isabella, Schiavo, Giampietro, Kremer, Eric J., Brito, Catarina, Alves, Paula M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367519/
https://ncbi.nlm.nih.gov/pubmed/26181626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2015.75
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