Corrective GUSB transfer to the canine mucopolysaccharidosis VII cornea using a helper-dependent canine adenovirus vector

Corneal transparency is maintained, in part, by specialized fibroblasts called keratocytes, which reside in the fibrous lamellae of the stroma. Corneal clouding, a condition that impairs visual acuity, is associated with numerous diseases, including mucopolysaccharidosis (MPS) type VII. MPS VII is d...

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Publicat a:J Control Release
Autors principals: Serratrice, Nicolas, Cubizolle, Aurelie, Ibanes, Sandy, Mestre-Francés, Nadine, Bayo-Puxan, Neus, Creyssels, Sophie, Gennetier, Aurelie, Bernex, Florence, Verdier, Jean-Michel, Haskins, Mark E., Couderc, Guilhem, Malecaze, Francois, Kalatzis, Vasiliki, Kremer, Eric J.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624437/
https://ncbi.nlm.nih.gov/pubmed/24607662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.02.022
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