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Renoprotective Effects of Aldose Reductase Inhibitor Epalrestat against High Glucose-Induced Cellular Injury

Diabetic nephropathy (DN) is the leading cause of end stage renal disease worldwide. Increased glucose flux into the aldose reductase (AR) pathway during diabetes was reported to exert deleterious effects on the kidney. The objective of this study was to investigate the renoprotective effects of AR...

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Bibliografiske detaljer
Udgivet i:Biomed Res Int
Main Authors: El Gamal, Heba, Eid, Ali Hussein, Munusamy, Shankar
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366186/
https://ncbi.nlm.nih.gov/pubmed/28386557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5903105
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