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Renoprotective Effects of Aldose Reductase Inhibitor Epalrestat against High Glucose-Induced Cellular Injury

Diabetic nephropathy (DN) is the leading cause of end stage renal disease worldwide. Increased glucose flux into the aldose reductase (AR) pathway during diabetes was reported to exert deleterious effects on the kidney. The objective of this study was to investigate the renoprotective effects of AR...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: El Gamal, Heba, Eid, Ali Hussein, Munusamy, Shankar
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366186/
https://ncbi.nlm.nih.gov/pubmed/28386557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5903105
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