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Renoprotective Effects of Aldose Reductase Inhibitor Epalrestat against High Glucose-Induced Cellular Injury

Diabetic nephropathy (DN) is the leading cause of end stage renal disease worldwide. Increased glucose flux into the aldose reductase (AR) pathway during diabetes was reported to exert deleterious effects on the kidney. The objective of this study was to investigate the renoprotective effects of AR...

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Библиографические подробности
Опубликовано в: :Biomed Res Int
Главные авторы: El Gamal, Heba, Eid, Ali Hussein, Munusamy, Shankar
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366186/
https://ncbi.nlm.nih.gov/pubmed/28386557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5903105
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