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Renoprotective Effects of Aldose Reductase Inhibitor Epalrestat against High Glucose-Induced Cellular Injury

Diabetic nephropathy (DN) is the leading cause of end stage renal disease worldwide. Increased glucose flux into the aldose reductase (AR) pathway during diabetes was reported to exert deleterious effects on the kidney. The objective of this study was to investigate the renoprotective effects of AR...

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Vydáno v:Biomed Res Int
Hlavní autoři: El Gamal, Heba, Eid, Ali Hussein, Munusamy, Shankar
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5366186/
https://ncbi.nlm.nih.gov/pubmed/28386557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5903105
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