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Distinct contributions of the thin and thick filaments to length-dependent activation in heart muscle

The Frank-Starling relation is a fundamental auto-regulatory property of the heart that ensures the volume of blood ejected in each heartbeat is matched to the extent of venous filling. At the cellular level, heart muscle cells generate higher force when stretched, but despite intense efforts the un...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Zhang, Xuemeng, Kampourakis, Thomas, Yan, Ziqian, Sevrieva, Ivanka, Irving, Malcolm, Sun, Yin-Biao
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365314/
https://ncbi.nlm.nih.gov/pubmed/28229860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24081
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