γδTCR immunoglobulin constant region domain exchange in human αβTCRs improves TCR pairing without altering TCR gene-modified T cell function

The adoptive genetic transfer of T cell receptors (TCRs) has been shown to be overall feasible and offer clinical potential as a treatment for different types of cancer. However, this promising clinical approach is limited by the serious potential consequence that exogenous TCR mispairing with endog...

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Vydáno v:Mol Med Rep
Hlavní autoři: Tao, Changli, Shao, Hongwei, Zhang, Wenfeng, Bo, Huaben, Wu, Fenglin, Shen, Han, Huang, Shulin
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365024/
https://ncbi.nlm.nih.gov/pubmed/28259946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6206
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