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γδTCR immunoglobulin constant region domain exchange in human αβTCRs improves TCR pairing without altering TCR gene-modified T cell function

The adoptive genetic transfer of T cell receptors (TCRs) has been shown to be overall feasible and offer clinical potential as a treatment for different types of cancer. However, this promising clinical approach is limited by the serious potential consequence that exogenous TCR mispairing with endog...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Med Rep
मुख्य लेखकों: Tao, Changli, Shao, Hongwei, Zhang, Wenfeng, Bo, Huaben, Wu, Fenglin, Shen, Han, Huang, Shulin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: D.A. Spandidos 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365024/
https://ncbi.nlm.nih.gov/pubmed/28259946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6206
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