Myeloid Cell-Specific Knockout of NFI-A Improves Sepsis Survival

Myeloid progenitor-derived suppressor cells (MDSCs) arise from myeloid progenitors and suppress both innate and adaptive immunity. MDSCs expand during the later phases of sepsis in mice, promote immunosuppression, and reduce survival. Here, we report that the myeloid differentiation-related transcri...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: McPeak, Melissa B., Youssef, Dima, Williams, Danielle A., Pritchett, Christopher, Yao, Zhi Q., McCall, Charles E., El Gazzar, Mohamed
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
Sujets:
Host Response and Inflammation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364314/
https://ncbi.nlm.nih.gov/pubmed/28167668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00066-17
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