Myeloid Cell-Specific Knockout of NFI-A Improves Sepsis Survival

Myeloid progenitor-derived suppressor cells (MDSCs) arise from myeloid progenitors and suppress both innate and adaptive immunity. MDSCs expand during the later phases of sepsis in mice, promote immunosuppression, and reduce survival. Here, we report that the myeloid differentiation-related transcri...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: McPeak, Melissa B., Youssef, Dima, Williams, Danielle A., Pritchett, Christopher, Yao, Zhi Q., McCall, Charles E., El Gazzar, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364314/
https://ncbi.nlm.nih.gov/pubmed/28167668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00066-17
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