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Myeloid Cell-Specific Knockout of NFI-A Improves Sepsis Survival

Myeloid progenitor-derived suppressor cells (MDSCs) arise from myeloid progenitors and suppress both innate and adaptive immunity. MDSCs expand during the later phases of sepsis in mice, promote immunosuppression, and reduce survival. Here, we report that the myeloid differentiation-related transcri...

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Библиографические подробности
Опубликовано в: :Infect Immun
Главные авторы: McPeak, Melissa B., Youssef, Dima, Williams, Danielle A., Pritchett, Christopher, Yao, Zhi Q., McCall, Charles E., El Gazzar, Mohamed
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364314/
https://ncbi.nlm.nih.gov/pubmed/28167668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00066-17
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