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Preclinical and Clinical Advances of GalNAc-Decorated Nucleic Acid Therapeutics
A main challenge in realizing the full potential of nucleic acid therapeutics is efficient delivery of them into targeted tissues and cells. N-acetylgalactosamine (GalNAc) is a well-defined liver-targeted moiety benefiting from its high affinity with asialoglycoprotein receptor (ASGPR). By conjugati...
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| Publicado en: | Mol Ther Nucleic Acids |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Gene & Cell Therapy
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5363494/ https://ncbi.nlm.nih.gov/pubmed/28325278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2016.12.003 |
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