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GalNAc-siRNA Conjugates: Leading the Way for Delivery of RNAi Therapeutics

Short-interfering RNA (siRNA)-induced RNAi responses have great potential to treat a wide variety of human diseases from cancer to pandemic viral outbreaks to Parkinson's Disease. However, before siRNAs can become drugs, they must overcome a billion years of evolutionary defenses designed to ke...

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Detalhes bibliográficos
Publicado no:Nucleic Acid Ther
Main Authors: Springer, Aaron D., Dowdy, Steven F.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994659/
https://ncbi.nlm.nih.gov/pubmed/29792572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2018.0736
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