Syngeneic AAV Pseudo-particles Potentiate Gene Transduction of AAV Vectors

Adeno-associated virus (AAV) vectors have emerged as a safe and efficient gene therapy platform. One complication is that a significant amount of empty particles have always been generated as impurities during AAV vector production. However, the effects of such particles on AAV vector performance re...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Ther Methods Clin Dev
Autori principali: Wang, Qizhao, Dong, Biao, Pokiniewski, Katie A., Firrman, Jenni, Wu, Zhongren, Chin, Mario P.S., Chen, Xiongwen, Liu, LinShu, Xu, Ruian, Diao, Yong, Xiao, Weidong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363323/
https://ncbi.nlm.nih.gov/pubmed/28345000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2016.12.004
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